ADEKUNLE, HALIMA ITUNU2024-12-192023https://dspace.summituniversity.edu.ng/handle/123456789/90Essential Oils (EOs) are concentrated natural extracts derived from plants, which were proved to be good source of antimicrobial properties. The study followed the effect of some commonly used essential oils against some of the most common pathogenic bacteria. The various oils used were Castor oil. Almond oil, Olive oil and Carrot oil against selected skin pathogens namely; Staphylococcus aureus, Corynebacterium diphtheria, Bacillus subtilis, Aeromonas and Pseudomonas aeruginosa. The collected isolates were confirmed using biochemical and microbiological tests. Carrot oil had the highest inhibiting activity against Bacilli and Corynebacterium with the value of 20mm while Almond oil and olive oil had no inhibition zone (NZ) against Corynebacterium and Pseudomonas. Ciprofloxacin was the control used and it showed significant inhibition against the clinical isolates. Olive oil had the lowest inhibition ranging from 5mm to 10mm. Combinatorial effect of the essential oils showed no antimicrobial activity against the isolates depicting antagonistic effects of the essential oils. In conclusion, carrot oil and castor oil had higher activity while almond oil and olive oil had the lowest activity against the selected clinical isolates.enArticle